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RESEARCH INTEREST

We develop chemical & biochemical tools to address fundamental problems in brain research

and explore  signaling pathway to understand complex biological systems for drug-discovery 

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ABOUT THE SUBJECTS
Development

Chemical &

Genetic tools

We are focusing on development of new technique to monitor interesting biological phenomena and identification of new small molecules to regulate biological system related to various neurological disease

  • Imaging probe

  • Chemical & Genetic screen

  • CRISPR gene-editing

  • Chemical modulators

Exploration

Pathway & Process

We want to explore complex signaling network to understand fundamental biological process and elucidate mode-of-action and mechanism-of-action for  interesting small molecules

  • Elucidation unknown function for interesting target

  • Understanding signaling pathway

  • Mode-of-action/Mechanism study of bioactive small-molecules

Discovery

New therapeutic approach

We are highly motivated by discovery of new therapeutic targets and potential drug-candidates for various neurological disorder to improve human health

  • Neurodegerative disease

  • Neuroinflammation

  • Brain tumor

FEATURE ARTICLES

Chem. Eng. J 2024

Assembly of 2′,3′-Cyclic guanosine Monophosphate-Adenosine
monophosphate and their spontaneous intracellular disassembly for
enhanced antitumor immunity via natural STING pathway activation

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L7435, 5, Hwarang-ro 14-gil, Seongbuk-gu, Seoul, Korea 02792

서울특별시 성북구 화랑로 14길 5, 뇌질환극복연구단 L7435호 ​(02792)

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